According to Sociedad Española de Neurología (SEN), Parkinson’s disease prevalence and incidence is increasing and estimated that the number of people affected will double in 20 years and triple in 2050.
This project addresses a new research line that aims to use data generated from smart insoles to objectively support an early treatment of Parkinson disease (PD) and consequently improve the life quality of patients.
To achieve these common objectives the project is divided into two sub-projects with complementary objectives. In the first one (MyGait_Bio) the measurement systems to obtain BCG and IPG signals will be designed and the signal processing will be developed to reduce the influence of the movement artifacts and to be able to extract all the cardiovascular information from the patient. The system for recharging the batteries of the smart insole based on inductive methods will also be designed. This platform will combine inductive battery recharging with the reading of measurement data stored in the memory of the measurement system.
In the second sub-project (MyGait_Sensors) the aim is to develop intelligent insoles that will allow, by means of force and inertial sensors and advanced algorithms, to monitor the patient’s gait and provide personalised information on the patient’s evolution. This second project also aims to realize experimental tests with clinical supervision that will validate the technologic systems developed and obtain the maximum clinical information.
Title: MyGait: Mejora de la calidad de vida de enfermos de Parkinson a través de plantillas inteligentes multisensores Duration: September 2021 – August 2024 Partners: ISI (UPC), HOWLAB (UZ) y B105 (UPM). Financing entity: Proyectos de I+D+i Retos Investigación, Ministerio de Ciencia e Innovación (PID2020-116011RB-C22)
The objective of the ESTAR project is to develop a system of completely autonomous low-cost devices that allow automatic monitoring through different sensors. The autonomy is based on the automation of the installation, energy harvesting and automatic configuration of both the network and the devices. In addition, the device will be easy to install and maintain.
The system will adapt to different use cases with different needs.
Title: ESTAR: Low-cost self-powered wireless multisensor devices for Industry 4.0 Duration: November 2022 – October 2023 Partners: UNIVERSIDAD POLITÉCNICA DE MADRID, CENTUM SOLUTIONS Financing entity: CENTUM SOLUTIONS con el apoyo del CENTRO PARA EL DESARROLLO TECNOLÓGICO Y LA INNOVACIÓN E.P.E. (CDTI) (IDI-20220872)
The general goal of the HUMAIN project is the improvement of production processes through industrial research and the creation of synergies for the achievement of novel methodologies and algorithms that allow:
Execute complex and diverse production processes with greater precision/quality.
Increase time efficiency and reduce unplanned stops (predictive maintenance system).
Optimize the use of resources, both material and energy.
Improve execution quality to help reduce waste generation at increasingly earlier stages of the production process in order to promote circularity.
The task of B105 Electronic Systems Lab is research into indoor and outdoor positioning systems for Industry 5.0.
Title: HUMAIN – Investigación de nuevas soluciones flexibles basadas en patrones de IA e IoT para una producción 5.0 más segura, eficiente y sostenible Duration: October 2022 – December 2024 Partners: GPA INNOVA, BAMA, CENTUM, AMPER S&C IOT, BitMetrics, UNIVERSIDAD POLITÉCNICA DE MADRID Financing entity: “Programa de Misiones de Ciencia e Innovación”, CENTRO PARA EL DESARROLLO TECNOLÓGICO Y LA INNOVACIÓN E.P.E. (CDTI) (MIP-20221036)
Neurotechnologies are achieving spectacular advances both in the treatment of pathologies of the nervous system (with the reduction of enormous social and economic costs associated with these diseases; with disability and mortality rates of 21M disabled, 1.2M deceased per year respectively in Europe, costs >4% of GDP) as well as in other important areas, such as empowerment and extension of brain capacities, brain-machine and brain-brain interfaces. The applications of these technologies are immense, from the clinical aspects related with the prevention, diagnosis and treatment of neurological pathologies to the development of new computation systems, improvement of learning, integration and connection of advanced devices with the nervous system.
The main goal of Madrid Innovative Neurotech Alliance (MINA-CM) is the innovation, development and application of advanced neurotechnological solutions in the Comunidad de Madrid.
The main objectives of MINA-CM are: The development of multidisciplinary and interinstitutional biomedical R+D+i in neurotechnologies for pathologies of the nervous system and improvement of brain capacities and interconnection through physical and functional interfaces. The attraction and incorporation of exceptional young researchers to R+D+i in neurotechnology in the Comunidad de Madrid. The reinforcement and enhancement of the participation of the Comunidad de Madrid in international networks and consortiums of R+D+I in neurotechnology. The reinforcement, potentiation and integration of companies, in particular SMEs of high technology in a network of R+D+i in neurotechnology in the Comunidad de Madrid to favor international and national funding.
Title: MINA-CM – Madrid Innovative Neurotech Alliance Duration: January 2023 – December 2026 Partners: UNIVERSIDAD POLITÉCNICA DE MADRID, UNIVERSIDAD COMPLUTENSE DE MADRID, CENTRO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS, HOSPITAL RAMÓN Y CAJAL, HOSPITAL CLÍNICO SAN CARLOS, HOSPITAL LA PAZ Financing entity: Comunidad de Madrid, Programas de actividades de I+D entre grupos de investigación de la Comunidad de Madrid en Biomedicina 2022 (P2022/BMD-7236)
Tenths of millions of people with organ failures or suffering from degenerative diseases are waiting for a novel cellular therapy or for a transplant of a donor compatible organ and the immense majority of these patients will die before receiving the tissue or organ they need. Despite the significant advances in tissue engineering, not a single artificial tissue has been used to replace a part of an organ, with the exception of simple or avascular tissues like skin or cartilage. And the main impediment is the up-to-date impossibility to engineer physiological vascular networks to provide O2 and nutrients to the artificial tissue.
THOR solves this drawback with the combination of self-assembling molecules (SAM) inspired to the Extracellular matrix (ECM) to construct solid and hollow polymeric fibers, spiderbots to create self-assembling structures (SAS) and photoactivable crosslinkers-based functionalization of the structures using SAM proteins. THOR tissue arises from high-resolution 3D spatial positioning of SAS, angiogenic factors and relevant cell lineages, reprogrammed and expanded in a dedicated bioreactor under controlled conditions.
B105 Electronics Systems Lab is in charge of the design and implementation of the spiderbots, as well as the integration with the rest of the technologies.
Title: THOR – Building vascular networks and Blood-Brain-Barriers through a Biomimetic manufacturing Technology for the fabrication of Human tissues and Organs Duration: January 2023 – December 2026 Partners: UNIVERSIDAD POLITÉCNICA DE MADRID, UNIVERSITAETSKLINIKUM FREIBURG, ELVESYS, UNIVERSITA DEGLI STUDI DELLA CAMPANIA LUIGI VANVITELLI, BIOACTIVE SURFACES, S.L. Financing entity: HORIZON-EIC-2022-PATHFINDEROPEN-01 (GA 101099719)